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The Hong Kong University of Science and Technology (
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Static protein binder designs typically lose nearly half their binding performance against alternate target conformations, but lightweight inference-time evolutionary adaptation cuts that degradation down to 4.4% in under three minutes without needing ensemble data.
Uncover hidden connections between broad biomedical knowledge and specific experimental data with SCENE, a framework that transforms general knowledge into testable, scenario-grounded hypotheses.
You can generate high-quality molecules that hit two targets at once, without the cost of retraining your generative model.