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Immunotherapy Research Center for Hematologic Diseases of Hubei Province, Wuhan, Hubei, China, Research Institute of Huazhong University of Science and Technology in Shenzhen, Shenzhen, China
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Dual-target CD19/CD22 CAR-T-cell therapy, especially when combined with ASCT, demonstrates sustained clinical benefit and may overcome the negative prognostic impact of TP53 alterations in relapsed/refractory aggressive B-NHL.