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Immunotherapy Research Center for Hematologic Diseases of Hubei Province, Wuhan, Hubei, China, MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition, University of Science and Technology of China
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Dual-target CD19/CD22 CAR-T-cell therapy, especially when combined with ASCT, demonstrates sustained clinical benefit and may overcome the negative prognostic impact of TP53 alterations in relapsed/refractory aggressive B-NHL.