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Max Planck Institute for Intelligent Systems, Max-Planck-Ring 4, 72076 T眉bingen, Germany, Max Planck Institute for Gravitational Physics (Albert Einstein Institute), Am M眉hlenberg 1, 14476 Potsdam, Germany
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Turns out, you *can* differentiate through the Gillespie algorithm: machine learning gradient estimators unlock parameter inference in stochastic kinetic models where traditional methods fail.