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A two-dimensional crystal melts via the proliferation and unbinding of topological defects, yet quantitatively predicting the melting temperature $T_m$ in real systems is challenging. Here we resolve this discrepancy in quantum Hall electron bubble phases by combining Corbino-geometry transport experiment in an ultraclean GaAs/AlGaAs quantum well for Landau levels 2 to 5 with Hartree--Fock elasticity and the full Kosterlitz--Thouless--Halperin--Nelson--Young melting criterion including the finite-temperature renormalization-group calculation. The theoretically obtained $T_m$ quantitatively captures the measured solid-liquid phase transition boundaries across all probed ranges, validating the bubble-crystal interpretation and establishing defect--mediated melting as a predictive framework for strongly interacting electronic solids. This agreement further supports using bulk transport to probe the energetics of topological defects and screening in quantum Hall physics, and the approach is readily extendable to other electronic crystals, including the generalized Wigner crystal in moir\'e Chern bands.