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The authors introduce MEDOPENCLAW, an auditable runtime environment, and MEDFLOWBENCH, a benchmark for evaluating VLMs on full, uncurated 3D medical imaging studies. This work addresses the limitations of current VLM evaluation in medical imaging, which relies on curated 2D images and fails to capture the complexities of real-world clinical diagnostics. Experiments reveal that while current LLMs/VLMs can navigate medical image viewers, their performance degrades when provided with professional-grade tools due to insufficient spatial grounding.
Giving medical imaging AIs the same tools as human doctors actually *hurts* their performance, revealing a surprising lack of spatial reasoning.
Currently, evaluating vision-language models (VLMs) in medical imaging tasks oversimplifies clinical reality by relying on pre-selected 2D images that demand significant manual labor to curate. This setup misses the core challenge of realworld diagnostics: a true clinical agent must actively navigate full 3D volumes across multiple sequences or modalities to gather evidence and ultimately support a final decision. To address this, we propose MEDOPENCLAW, an auditable runtime designed to let VLMs operate dynamically within standard medical tools or viewers (e.g., 3D Slicer). On top of this runtime, we introduce MEDFLOWBENCH, a full-study medical imaging benchmark covering multi-sequence brain MRI and lung CT/PET. It systematically evaluates medical agentic capabilities across viewer-only, tool-use, and open-method tracks. Initial results reveal a critical insight: while state-of-the-art LLMs/VLMs (e.g., Gemini 3.1 Pro and GPT-5.4) can successfully navigate the viewer to solve basic study-level tasks, their performance paradoxically degrades when given access to professional support tools due to a lack of precise spatial grounding. By bridging the gap between static-image perception and interactive clinical workflows, MEDOPENCLAW and MEDFLOWBENCH establish a reproducible foundation for developing auditable, full-study medical imaging agents.