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School of Mathematics and Statistics, Lanzhou University, 222 South Tianshui Road, Lanzhou 730000, Gansu, China, Department of Computer Science, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong 999077, China
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Generate better peptide therapeutics faster: a new deep learning framework predicts peptide-protein interactions with high accuracy and generates novel peptides with enhanced binding affinity.
Unlocking the black box of DNA methylation prediction, MEDNA-DFM reveals a "sequence-structure synergy" where GAGG core motifs and upstream A-tract elements cooperate, a hypothesis validated by in silico experiments.
