M. Wunderlich

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Mingjun Cai (1)Xin Duan (1)Ryan Jorgensen (1)F. Guo (1)

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Feb 18, 2026

1Cincinnati Children's Hospital Medical Center3w ago

Abstract B013: Targeting CDC42 increases TCF1-mediated “stemness” and rejuvenates human T cells to enhance CAR-T efficacy

Targeting CDC42 with CASIN rejuvenates T cells, increasing stemness and enhancing CAR-T cell efficacy, suggesting a novel approach to improve cancer immunotherapy.

Mingjun Cai, Xin Duan, Ryan Jorgensen +3

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M. Wunderlich

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