Sigrun Roeber

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Julien Klimmt (1)Carolina Cardoso Gonçalves (1)J. V. Montgomery (1)Stephan A. Müller (1)Merle Bublitz (1)S. Filser (1)L. Paeger (1)B. Nuscher (1)

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Aug 4, 2026

Julien Klimmt +26Aug 4, 2026

A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes.

A human induced pluripotent stem cell-based three-dimensional cortical brain tissue model (3BTM) containing neurons, astrocytes and microglia with high reproducibility, maturity and viability that recapitulate key disease hallmarks when engineered to model Alzheimer's disease pathology.

Julien Klimmt, Carolina Cardoso Gonçalves, J. V. Montgomery +24

Sigrun Roeber

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Sigrun Roeber

Frequent co-authors

Papers (1)