Surgical treatment of metastatic colorectal cancer

Aim. Using data from research studies, to analyze the efficacy and safety of performing simultaneous surgeries for synchronous colorectal cancer metastases to the liver, and to identify risk factors for postoperative complications. Since the early 2000s, hepatectomy has been the standard procedure for treating metastatic colorectal cancer, resulting in significantly higher survival rates than systemic therapy alone. Currently, treatment approaches, such as tumor-first, liverfirst, or combined, are not standardized. The treatment strategy for synchronous colorectal cancer metastases depends on tumor location, symptom presence, and experience of the medical center. The incidence of surgical complications following simultaneous surgeries is comparable to that of staged surgeries. This finding confirms the effectiveness and safety of simultaneous surgeries when patients are carefully selected. Simultaneous surgeries are major procedures that are not suitable for all patients. The decision to perform them should be made prior to hospital admission while considering risk factors for postoperative complications.