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A progressive four-stage framework that addresses three clinically critical gaps in TCM prescription generation and substantially improves prescription quality over zero-shot baselines is proposed, with a 7B model (Mistral-7B) surpassing zero-shot GPT-5 on all three TCM evaluation metrics.
TCMaster is presented, a property-graph query substrate for confidence-aware traversal and workload-guided physical design over Traditional Chinese Medicine KGs, which integrates pharmacopoeias, prescriptions, molecular databases, and LLM-extracted micro-semantics into a KG with approximately 221K entities and 723K base edges.